OPTICAL PROJECTION TOMOGRAPHY REVEALS DYNAMICS OF HEV GROWTH AFTER IMMUNIZATION WITH PROTEIN PLUS CFA AND FEATURES SHARED WITH HEVS IN ACUTE AUTOINFLAMMATORY LYMPHADENOPATHY

Optical projection tomography reveals dynamics of HEV growth after immunization with protein plus CFA and features shared with HEVs in acute autoinflammatory lymphadenopathy

The vascular-stromal compartment of lymph nodes is important for lymph node function, and high endothelial venules (HEVs) play a critical role in controlling the entry of recirculating lymphocytes.In autoimmune and autoinflammatory diseases, lymph node swelling is often accompanied by apparent HEV expansion and, potentially, targeting HEV expansion

read more



Systematic Review of Soft Tissue Sarcomas in Latin America

PURPOSESoft tissue sarcomas (STSs) are rare malignant neoplasms posing significant public health challenges globally, especially in Latin America with limited research resources.This systematic review provides an overview of the epidemiology, clinical characteristics, treatment, and outcomes of STSs in Engraved Leather Belt Latin America, emphasizi

read more

Artemisinin-Based Combination Therapy Depressed Mitosis and Induced Chromosome Aberration in Onion Root Cells

Artemisinin-based combination therapy is used to treat uncomplicated malaria disease in most endemic countries.Although most antimalarial drugs are effective in killing the parasite, there is a concern of induced toxicity to the cell.Here, the cytogenotoxicity of dihydroartemisinin-piperaquine phosphate (DHAP), a coformulation for artemisinin-based

read more